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Search Result

Search Results for " papain-like protease "

Targets

SARS-CoV

9

Compounds

1

Natural Products

8

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T9606 TC-067533 SARS-CoV
TC-067533 is a Papain-like protease inhibitor with an IC50 of 8.7 μM.
T12502 PLpro inhibitor SARS-CoV
PLpro inhibitor is a potent papain-like protease (PLpro) inhibitor(IC50 of 2.6 uM)
T78704 PLpro/RBD-IN-1 SARS-CoV
PLpro/RBD-IN-1 (Compound 5) serves as a dual inhibitor targeting both the SARS-CoV-2 papain-like protease (PLpro) and the receptor-binding domain (RBD) of the spike protein, exhibiting half-maximal inhibitory concentrati...
T36352 Suc-Leu-Tyr-AMC
Suc-Leu-Tyr-AMC is a fluorescent substrate for calpain I and II and papain (another cysteine protease) that is used for measuring the chymotrypsin-like peptidase activity of the 20S proteasome (excitation max: 360 nm; em...
T18911 Acriflavine Acriflavinium chloride 3,6-Acridinediamine mix SARS-CoV , Antibacterial
Acriflavine (Acriflavinium chloride 3,6-Acridinediamine mix) is a papain-like protease (PL(pro)) inhibitor, a fluorescent dye for labeling high molecular weight RNAs, has antimicrobial and anticancer activity, inhibits S...
T61500 PLP_Snyder530
PLP_Snyder530 is a potent papain-like protease (PL pro ) inhibitor. PLP_Snyder530 induces conformational changes in SARS-COV-2 papain-like protease, inhibiting SARS-CoV-2 replication. PLP_Snyder530 can be used for SARS-C...
T63443 XR8-89
XR8-89, a potent inhibitor of papain-like protease (PLpro), exhibits an IC50 value of 0.1 μM and effectively hinders SARS-CoV-2 replication by inducing conformational changes in the SARS-COV-2 papain-like protease. This ...
T60841 SARS-CoV-2-IN-23
SARS-CoV-2-IN-23 (compound GRL-0617) is an inhibitor of SARS-COV-2 papain-like protease (PLpro) (IC 50 = 2.3 μM) [1].
T81202 SARS-CoV-2-IN-69 SARS-CoV
SARS-CoV-2-IN-69 (Compound 7E) is a potent, non-covalent inhibitor of the SARS-CoV-2 main protease (M^pro) with an EC50 of 7.4 μM and also inhibits the papain-like protease (PL^pro) [1].
Cat No. Product Name Synonyms Targets
T3S0136 4'-O-Methylbavachalcone O-Methylbroussochalcone B SARS-CoV
4'-O-Methylbavachalcone (O-Methylbroussochalcone B) is isolated from Psoralea corylifolia, inhibits severe acute respiratory syndrome coronavirus (SARS-CoV) papain-like protease (PLpro) activity (IC50: 10.1 μM).

Natural Products

4'-O-Methylbavachalcone
T3S0136
Synonym: O-Methylbroussochalcone B
Target: SARS-CoV

Recombinant Proteins

Species：
Human (3)
SARS (3)
SARS-CoV-2 (2)
Expression System：
E. coli (5)
HEK293 Cells (3)
Tag：
His (3)
C-His (2)
N-His (1)
N-His-Avi (1)
Tag Free (1)
Cat No. Product Name Species Expression System
TMPJ-01431 SARS-CoV-2 Papain-Like Protease Protein SARS-CoV-2 E. coli
Replication of severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) requires proteolytic processing of the replicase polyprotein by two viral cysteine proteases, a chymotrypsin-like protease (3CLpro) and a pap...
TMPK-01384 SARS PLpro/papain-like protease Protein (His) SARS E. coli
The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. Although the primary function of PLpro ...
TMPK-01352 SARS-CoV-2 PLpro/papain-like protease Protein (His & Avi) SARS E. coli
The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. Although the primary function of PLpro ...
TMPY-04894 SARS-CoV (strain WH20) Plpro/papain-like protease (His) SARS E. coli
SARS-CoV (strain WH20) Plpro/papain-like protease (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 36.65 kDa and the accession number is AAX16193.1.
TMPY-05682 SARS-CoV-2 Plpro/papain-like protease Protein (aa 1564-1880, His) SARS-CoV-2 E. coli
SARS-CoV-2 Plpro/papain-like protease Protein (aa 1564-1880, His) is expressed in E. coli expression system. The predicted molecular weight is 36.79 kDa and the accession number is QVD65746.1.
TMPY-01644 Cystatin S Protein, Human, Recombinant (His) Human HEK293 Cells
Cystatin-S, also known as Cystatin-4, Salivary acidic protein 1, Cystatin-SA-III and CST4, is a secreted protein which belongs to thecystatin family. Cystatin-4 / CST4 is expressed in submandibular and sublingual sali...
TMPY-02070 Cystatin SN Protein, Human, Recombinant (His) Human HEK293 Cells
Cystatin-SN, also known as Cystain-SA-I, Cystatin-1, Salivary cystatin-SA-1 and CST1, is a secreted protein which belongs to thecystatin family. The cystatin superfamily encompasses proteins that contain multiple cyst...
TMPY-01249 Cathepsin V Protein, Human, Recombinant (His) Human HEK293 Cells
Cathepsin V (CTSV), also known as Cathepsin L2, CTSL2, and CATL2, is a member of the peptidase C1 family. It is predominantly expressed in the thymus and testis. Cathepsin V is also expressed in corneal epithelium, and t...
Cat No. Product Name
L1710 Anti-COVID-19 Compound Library

1133 compounds
A unique collection of 1133 compounds with confirmed anti-SARS-CoV-2 activity or potential activity and part of them are broad-spectrum antiviral agents；

Libraries

Anti-COVID-19 Compound Library
L1710
Compounds: 1133
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